Functionalized biomimetic calcium phosphates for bone tissue repair

被引：62

作者：

Bigi, Adriana ^{[1
]}

Boanini, Elisa ^{[1
]}

机构：

[1] Univ Bologna, Dept Chem G Ciamician, Via Selmi 2, I-40126 Bologna, Italy

来源：

JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS | 2017年 / 15卷 / 04期

关键词：

Bone cements; Calcium phosphates; Coatings; Drug delivery; Hydroxyapatite; Scaffolds; OSTEOBLAST-LIKE CELLS; SILICON-SUBSTITUTED HYDROXYAPATITE; BETA-TRICALCIUM PHOSPHATE; PULSED-LASER EVAPORATION; IN-VITRO RESPONSE; DRUG-DELIVERY; MECHANICAL-PROPERTIES; NANOCRYSTALLINE APATITES; DOPED HYDROXYAPATITE; MOLECULAR-MECHANISMS;

D O I：

10.5301/jabfm.5000367

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 [生物物理学];

摘要：

The design and development of novel materials for biomineralized tissues is an extremely attractive field of research where calcium phosphates (CaPs)-based materials for biomedical applications play a leading role. The biological performance of these compounds can be enhanced through functionalization with biologically active ions and molecules. This review reports on some important recent achievements in creating functionalized biomimetic CaP materials for applications in the musculoskeletal field. Particular attention is focused on the modifications of these inorganic compounds with bioactive ions, growth factors and drugs, as well as on recent trends in some important CaP applications as biomaterials - namely, as bone cements, coatings of metallic implants and scaffolds for regenerative medicine.

引用

收藏

页码：E313 / E325

页数：13

相关论文

共 179 条

[1]

Multi-Layered Scaffolds for Osteochondral Tissue Engineering: In Vitro Response of Co-Cultured Human Mesenchymal Stem Cells [J].

Amadori, Sofia ;

Torricelli, Paola ;

Panzavolta, Silvia ;

Parrilli, Annapaola ;

Fini, Milena ;

Bigi, Adriana .

MACROMOLECULAR BIOSCIENCE, 2015, 15 (11) :1535-1545

[2]

Strontium ranelate: A novel mode of action leading to renewed bone quality [J].

Ammann, P .

OSTEOPOROSIS INTERNATIONAL, 2005, 16 (Suppl 1) :S11-S15

[3]

[Anonymous], 2001, Biomineralization: Principles and Concepts in Bioinorganic Materials Chemistry

[4]

Acceleration of apatite nucleation on microrough bioactive titanium for bone-replacing implants [J].

Aparicio, C. ;

Manero, J. M. ;

Conde, F. ;

Pegueroles, M. ;

Planell, J. A. ;

Vallet-Regi, M. ;

Gil, F. J. .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2007, 82A (03) :521-529

[5]

Structural differences between "dark" and "bright" isolated human osteonic lamellae [J].

Ascenzi, MG ;

Ascenzi, A ;

Benvenuti, A ;

Burghammer, M ;

Panzavolta, S ;

Bigi, A .

JOURNAL OF STRUCTURAL BIOLOGY, 2003, 141 (01) :22-33

[6]

Mediating bone regeneration by means of drug eluting implants: From passive to smart strategies [J].

Bagherifard, Sara .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 71 :1241-1252

[7]

Bioinspired large-scale aligned porous materials assembled with dual temperature gradients [J].

Bai, Hao ;

Chen, Yuan ;

Delattre, Benjamin ;

Tomsia, Antoni P. ;

Ritchie, Robert O. .

SCIENCE ADVANCES, 2015, 1 (11)

[8]

Effects of electrospun submicron fibers in calcium phosphate cement scaffold on mechanical properties and osteogenic differentiation of umbilical cord stem cells [J].

Bao, Chongyun ;

Chen, Wenchuan ;

Weir, Michael D. ;

Thein-Han, Wahwah ;

Xu, Hockin H. K. .

ACTA BIOMATERIALIA, 2011, 7 (11) :4037-4044

[9]

Advanced biomaterials for skeletal tissue regeneration:: Instructive and smart functions [J].

Barrere, F. ;

Mahmood, T. A. ;

de Groot, K. ;

van Blitterswijk, C. A. .

MATERIALS SCIENCE & ENGINEERING R-REPORTS, 2008, 59 (1-6) :38-71

[10]

Osteointegration of biomimetic apatite coating applied onto dense and porous metal implants in femurs of goats [J].

Barrère, F ;

van der Valk, CM ;

Meijer, G ;

Dalmeijer, RAJ ;

de Groot, K ;

Layrolle, P .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2003, 67B (01) :655-665

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