Selfish genetic elements, genetic conflict, and evolutionary innovation

被引：295

作者：

Werren, John H. ^{[1
]}

机构：

[1] Univ Rochester, Dept Biol, Rochester, NY 14627 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2011年 / 108卷

基金：

美国国家科学基金会;

关键词：

RESTRICTION-MODIFICATION SYSTEMS; TRANSPOSABLE ELEMENTS; MEIOTIC-DRIVE; GENOME EVOLUTION; INTRAGENOMIC CONFLICT; EUKARYOTIC EVOLUTION; HORIZONTAL TRANSFER; HYBRID STERILITY; DNA METHYLATION; MOBILE ELEMENTS;

D O I：

10.1073/pnas.1102343108

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Genomes are vulnerable to selfish genetic elements (SGEs), which enhance their own transmission relative to the rest of an individual's genome but are neutral or harmful to the individual as a whole. As a result, genetic conflict occurs between SGEs and other genetic elements in the genome. There is growing evidence that SGEs, and the resulting genetic conflict, are an important motor for evolutionary change and innovation. In this review, the kinds of SGEs and their evolutionary consequences are described, including how these elements shape basic biological features, such as genome structure and gene regulation, evolution of new genes, origin of new species, and mechanisms of sex determination and development. The dynamics of SGEs are also considered, including possible "evolutionary functions" of SGEs.

引用

页码：10863 / 10870

页数：8

共 88 条

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