Immunosuppressive diterpenes from Veronicastrum sibiricum

被引：18

作者：

Gao, WY

Zhang, R

Jia, W

Zhang, J

Takaishi, Y

Duan, HQ ^{[1
]}

机构：

[1] Tianjin Univ, Coll Pharmaceut & Biotechnol, Tianjin 300072, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200030, Peoples R China

[3] Tianjin Med Univ, Sch Pharm, Tianjin 300070, Peoples R China

[4] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 7708505, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2004年 / 52卷 / 01期

关键词：

Veronicastrum sibiricum; diterpene; immunosuppressive activity;

D O I：

10.1248/cpb.52.136

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new diterpenes, named sibiriquinone A (1) and B (2), along with four known diterpenes have been isolated from the aerial part of Veronicastrum sibiricum. Their structures were elucidated by spectroscopy. The isolated compounds showed significant immunosuppressive activities.

引用

页码：136 / 137

页数：2

共 9 条

[1]

Fang Q. N., 1976, ACTA CHIM SINICA, V34, P197

[2]

Fletcher MA, 1992, Manual of Clinical Laboratory Immunology, V4th, P213

[3] Terpenoids from Tripterigyum hypoglaucum [J].

Fujita, R ;

Duan, HQ ;

Takaishi, Y .

PHYTOCHEMISTRY, 2000, 53 (06) :715-722

[4]

LUO HW, 1986, CHEM PHARM BULL, V34, P3166

[5] PIGMENTS FROM SALVIA-MILTIORRHIZA [J].

LUO, HW ;

WU, BJ ;

WU, MY ;

YONG, ZG ;

NIWA, M ;

HIRATA, Y .

PHYTOCHEMISTRY, 1985, 24 (04) :815-817

[6]

NAKANISHI T, 1983, PHYTOCHEMISTRY, V22, P721, DOI 10.1016/S0031-9422(00)86969-1

[7]

ZHANG JT, 1998, MODERN PHARM EXPT ME, P701

[8]

ZHOU BX, 1992, CHINESE PHARM J, V17, P493

[9]

1998, ZHONGHUABENCAO, V7, P414

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