Molecularly imprinted drug delivery systems

被引：215

作者：

Cunliffe, D

Kirby, A

Alexander, C

机构：

[1] Univ Portsmouth, Sch Pharm & Biomed Sci, Portsmouth PO1 2DT, Hants, England

[2] Univ Portsmouth, Inst Biomed & Biomol Sci, Portsmouth PO1 2DT, Hants, England

[3] Mol Recognit Mat Ltd, Cardiff CF1 3XF, S Glam, Wales

[4] Univ Nottingham, Sch Pharm, Nottingham NG7 2RD, England

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2005年 / 57卷 / 12期

基金：

英国工程与自然科学研究理事会;

关键词：

imprinted polymers; cross-linked matrices; controlled release; molecular recognition; drug delivery; MIP;

D O I：

10.1016/j.addr.2005.07.015

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Imprinted polymers are well established as molecular recognition materials but are now being increasingly considered for active biomedical applications such as drug delivery. In this review some highlights of recent research into molecularly imprinted drug delivery and controlled release systems are presented. The key factors controlling recognition and release by imprinted polymer matrices are discussed, the current limiting factors in their properties arising from the synthesis of these materials are considered, and the future prospects for imprinted polymers in drug delivery are outlined. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：1836 / 1853

页数：18

共 132 条

[1] Selective adsorption of dibenzothiophene sulfone by an imprinted and stimuli-responsive chitosan hydrogel [J].