Relapse of chronic myeloid leukaemia 14 years after allogeneic bone marrow transplantation

被引:30
作者
Yong, ASM [1 ]
Goldman, JM [1 ]
机构
[1] Hammersmith Hosp, Imperial Coll, Sch Med, Dept Haematol, London W12 0NN, England
关键词
late relapse; chronic myeloid leukaemia; bone marrow transplantation;
D O I
10.1038/sj.bmt.1701729
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Allogeneic bone marrow transplantation (BMT) is the treatment of choice for patients with chronic myeloid leukaemia (CML) who are relatively young and have suitable donors. Relapse is rare more than 5 years after allografting. We describe a patient who relapsed with myeloid blast transformation 14 years after allografting. This case suggests that leukaemia stem cells may on occasion remain quiescent for long periods and emphasises the importance of long-term follow-up after transplantation for CML.
引用
收藏
页码:827 / 828
页数:2
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