Decreased effectiveness of metronidazole for the treatment of Clostridium difficile infection?

被引:49
作者
Kuijper, Ed J. [1 ]
Wilcox, Mark H. [2 ,3 ]
机构
[1] Leiden Univ, Med Ctr, Dept Med Microbiol, Natl Reference Lab Clostridium Difficile, NL-2300 RC Leiden, Netherlands
[2] Leeds Teaching Hosp, Dept Med Microbiol, Leeds, W Yorkshire, England
[3] Univ Leeds, Leeds, W Yorkshire, England
关键词
D O I
10.1086/588294
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:63 / 65
页数:3
相关论文
共 25 条
[1]   Comparison of clinical and microbiological response to treatment of Clostridium difficile associated disease with metronidazole and vancomycin [J].
Al-Nassir, Wafa N. ;
Sethi, Ajay K. ;
Nerandzic, Michelle M. ;
Bobulsky, Greg S. ;
Jump, Robin L. P. ;
Donskey, Curtis J. .
CLINICAL INFECTIOUS DISEASES, 2008, 47 (01) :56-62
[2]  
[Anonymous], 2007, Clin Infect Dis
[3]   Antimicrobial susceptibility pattern of Clostridium difficile and its relation to PCR ribotypes in a Swedish University Hospital [J].
Aspevall, O ;
Lundberg, A ;
Burman, LG ;
Åkerlund, T ;
Svenungsson, B .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (05) :1890-1892
[5]   Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates [J].
Barbut, F. ;
Mastrantonio, P. ;
Delmee, M. ;
Brazier, J. ;
Kuijper, E. ;
Poxton, I. .
CLINICAL MICROBIOLOGY AND INFECTION, 2007, 13 (11) :1048-1057
[6]   FECAL METRONIDAZOLE CONCENTRATIONS DURING ORAL AND INTRAVENOUS THERAPY FOR ANTIBIOTIC ASSOCIATED COLITIS DUE TO CLOSTRIDIUM-DIFFICILE [J].
BOLTON, RP ;
CULSHAW, MA .
GUT, 1986, 27 (10) :1169-1172
[7]  
Centers for Disease Control and Prevention, Infection control in healthcare settings
[8]  
ELLAMES D, 2007, 47 INT C ANT AG CHEM
[9]   First cluster of clindamycin-resistant Clostridium difficile PCR ribotype 027 in Switzerland [J].
Fenner, L. ;
Widmer, A. F. ;
Stranden, A. ;
Conzelmann, M. ;
Goorhuis, A. ;
Harmanus, C. ;
Kuijper, E. J. ;
Frei, R. .
CLINICAL MICROBIOLOGY AND INFECTION, 2008, 14 (05) :514-515
[10]   Effect of metronidazole on growth and toxin production by epidemic Clostridium difficile PCR ribotypes 001 and 027 in a human gut model [J].
Freeman, Jane ;
Baines, Simon D. ;
Saxton, Katie ;
Wilcox, Mark H. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 60 (01) :83-91