Cross-presentation: avoiding trafficking chaos?

被引:18
作者
Kasturi, Sudhir Pai [1 ]
Pulendran, Bali [1 ]
机构
[1] Emory Vaccine Ctr, Atlanta, GA 30329 USA
关键词
D O I
10.1038/ni0508-461
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cross-presentation of antigens is essential for the responses of cytotoxic T cells to tumors and viruses. Two new papers offer insights into the subcellular compartment and types of dendritic cells that mediate cross-presentation.
引用
收藏
页码:461 / 463
页数:4
相关论文
共 14 条
[1]   Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens [J].
Ackerman, AL ;
Kyritsis, C ;
Tampé, R ;
Cresswell, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (22) :12889-12894
[2]   Cross-priming [J].
Bevan, MJ .
NATURE IMMUNOLOGY, 2006, 7 (04) :363-365
[3]   CROSS-PRIMING FOR A SECONDARY CYTOTOXIC RESPONSE TO MINOR H-ANTIGENS WITH H-2 CONGENIC CELLS WHICH DO NOT CROSS-REACT IN CYTOTOXIC ASSAY [J].
BEVAN, MJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 1976, 143 (05) :1283-1288
[4]   Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation [J].
Burgdorf, Sven ;
Schoelz, Christian ;
Kautz, Andreas ;
Tampe, Robert ;
Kurts, Christian .
NATURE IMMUNOLOGY, 2008, 9 (05) :558-566
[5]   Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation [J].
Burgdorf, Sven ;
Kautz, Andreas ;
Boehnert, Volker ;
Knolle, Percy A. ;
Kurts, Christian .
SCIENCE, 2007, 316 (5824) :612-616
[6]   CD8+ but not CD8- dendritic cells cross-prime cytotoxic T cells in vivo [J].
den Haan, JMM ;
Lehar, SM ;
Bevan, MJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (12) :1685-1695
[7]   Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I [J].
Di Pucchio, Tiziana ;
Chatterjee, Bithi ;
Smed-Sorensen, Anna ;
Clayton, Sandra ;
Palazzo, Adam ;
Montes, Monica ;
Xue, Yaming ;
Mellman, Ira ;
Banchereau, Jacques ;
Connolly, John E. .
NATURE IMMUNOLOGY, 2008, 9 (05) :551-557
[8]   Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages [J].
Gagnon, E ;
Duclos, S ;
Rondeau, C ;
Chevet, E ;
Cameron, PH ;
Steele-Mortimer, O ;
Paiement, J ;
Bergeron, JJM ;
Desjardins, M .
CELL, 2002, 110 (01) :119-131
[9]   ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells [J].
Guermonprez, P ;
Saveanu, L ;
Kleijmeer, M ;
Davoust, J ;
van Endert, P ;
Amigorena, S .
NATURE, 2003, 425 (6956) :397-402
[10]   Antigen crosspresentation by human plasmacytoid dendritic cells [J].
Hoeffel, Guillaume ;
Ripoche, Anne-Claire ;
Matheoud, Diana ;
Nascimbeni, Michelina ;
Escriou, Nicolas ;
Lebon, Pierre ;
Heshmati, Farhad ;
Guillet, Jean-Gerard ;
Gannage, Monique ;
Caillat-Zucman, Sophie ;
Casartelli, Nicoletta ;
Schwartz, Olivier ;
De la Salle, Henri ;
Hanau, Daniel ;
Hosmalin, Anne ;
Maranon, Concepcion .
IMMUNITY, 2007, 27 (03) :481-492