Association of the urease gene with enterohemorrhagic Escherichia coli strains irrespective of their serogroups

被引：33

作者：

Nakano, M

Iida, T

Ohnishi, M

Kurokawa, K

Takahashi, A

Tsukamoto, T

Yasunaga, T

Hayashi, T

Honda, T

机构：

[1] Osaka Univ, Microbial Dis Res Inst, Dept Bacterial Infect, Suita, Osaka 5650871, Japan

[2] Osaka Univ, Genome Informat Res Ctr, Osaka, Japan

[3] Miyazaki Med Coll, Dept Microbiol, Miyazaki 88916, Japan

[4] Univ Tokushima, Sch Med, Dept Nutr, Tokushima 770, Japan

[5] Osaka Prefectural Inst Publ Hlth, Osaka 537, Japan

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2001年 / 39卷 / 12期

关键词：

D O I：

10.1128/JCM.39.12.4541-4543.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Among various diarrheagenic Escherichia coli strains from clinical sources, we found that the urease gene was specifically associated with enterohemorrhagic E. coli (EHEC) strains irrespective of their serogroups. The results suggest that the urease gene can be a useful genetic marker for the detection of EHEC strains and for the diagnosis of infections caused by EHEC strains in the clinical situation.

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页码：4541 / 4543

页数：3

相关论文

共 13 条

[1] AIDA-I, THE ADHESIN INVOLVED IN DIFFUSE ADHERENCE OF THE DIARRHEOGENIC ESCHERICHIA-COLI STRAIN-2787 (O126-H27), IS SYNTHESIZED VIA A PRECURSOR MOLECULE [J].

BENZ, I ;

SCHMIDT, MA .

MOLECULAR MICROBIOLOGY, 1992, 6 (11) :1539-1546

[2] The complete genome sequence of Escherichia coli K-12 [J].

Blattner, FR ;

Plunkett, G ;

Bloch, CA ;

Perna, NT ;

Burland, V ;

Riley, M ;

ColladoVides, J ;

Glasner, JD ;

Rode, CK ;

Mayhew, GF ;

Gregor, J ;

Davis, NW ;

Kirkpatrick, HA ;

Goeden, MA ;

Rose, DJ ;

Mau, B ;

Shao, Y .

SCIENCE, 1997, 277 (5331) :1453-+

[3] GENETIC-ANALYSIS OF ESCHERICHIA-COLI UREASE GENES - EVIDENCE FOR 2 DISTINCT LOCI [J].

COLLINS, CM ;

FALKOW, S .

JOURNAL OF BACTERIOLOGY, 1990, 172 (12) :7138-7144

[4] GENETIC-ANALYSIS OF AN ESCHERICHIA-COLI UREASE LOCUS - EVIDENCE OF DNA REARRANGEMENT [J].

COLLINS, CM ;

FALKOW, S .

JOURNAL OF BACTERIOLOGY, 1988, 170 (03) :1041-1045

[5] THE PLASMID-ENCODED UREASE GENE-CLUSTER OF THE FAMILY ENTEROBACTERIACEAE IS POSITIVELY REGULATED BY URER, A MEMBER OF THE ARAC FAMILY OF TRANSCRIPTIONAL ACTIVATORS [J].

DORAZIO, SEF ;

COLLINS, CM .

JOURNAL OF BACTERIOLOGY, 1993, 175 (11) :3459-3467

[6] NUCLEOTIDE-SEQUENCE OF THE SURFACE EXCLUSION GENES TRAS AND TRAT FROM THE INCF0 LAC PLASMID-PED208 [J].

FINLAY, BB ;

PARANCHYCH, W .

JOURNAL OF BACTERIOLOGY, 1986, 166 (03) :713-721

[7]

Hayashi T, 2001, DNA RES, V8, P11, DOI 10.1093/dnares/8.1.11

[8] PURIFICATION AND CHARACTERIZATION OF KLEBSIELLA-AEROGENES UREE PROTEIN - A NICKEL-BINDING PROTEIN THAT FUNCTIONS IN UREASE METALLOCENTER ASSEMBLY [J].

LEE, MH ;

PANKRATZ, HS ;

WANG, S ;

SCOTT, RA ;

FINNEGAN, MG ;

JOHNSON, MK ;

IPPOLITO, JA ;

CHRISTIANSON, DW ;

HAUSINGER, RP .

PROTEIN SCIENCE, 1993, 2 (06) :1042-1052

[9] SEQUENCE OF THE KLEBSIELLA-AEROGENES UREASE GENES AND EVIDENCE FOR ACCESSORY PROTEINS FACILITATING NICKEL INCORPORATION [J].

MULROONEY, SB ;

HAUSINGER, RP .

JOURNAL OF BACTERIOLOGY, 1990, 172 (10) :5837-5843

[10] Iha:: a novel Escherichia coli O157:H7 adherence-conferring molecule encoded on a recently acquired chromosomal island of conserved structure [J].

Tarr, PI ;

Bilge, SS ;

Vary, JC ;

Jelacic, S ;

Habeeb, RL ;

Ward, TR ;

Baylor, MR ;

Besser, TE .

INFECTION AND IMMUNITY, 2000, 68 (03) :1400-1407