In vitro susceptibilities of Chlamydia pneumoniae strains recovered from atherosclerotic coronary arteries

被引：31

作者：

Gieffers, J ^{[1
]}

Solbach, W ^{[1
]}

Maass, M ^{[1
]}

机构：

[1] Univ Lubeck, Inst Med Microbiol & Hyg, D-23538 Lubeck, Germany

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1998年 / 42卷 / 10期

关键词：

D O I：

10.1128/AAC.42.10.2762

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Chlamydia pneumoniae strains have been recovered from arteriosclerotic coronary arteries, but their antibiotic susceptibility profiles have not get been examined, We report in vitro susceptibility data for five cardiovascular C. pneumoniae isolates. These strains did not differ significantly from respiratory strains in their patterns of susceptibility to azithromycin, erythromycin, roxithromycin, ofloxacin, doxycycline, rifampin, and penicillin G. Roxithromycin was the most active macrolide, and rifampin was the most effective drug overall.

引用

页码：2762 / 2764

页数：3

共 19 条

[1] DETECTION OF CHLAMYDIA-PNEUMONIAE TWAR IN HUMAN CORONARY ATHERECTOMY TISSUES [J].

CAMPBELL, LA ;

OBRIEN, ER ;

CAPPUCCIO, AL ;

KUO, CC ;

WANG, SP ;

STEWART, D ;

PATTON, DL ;

CUMMINGS, PK ;

GRAYSTON, JT .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (02) :585-588

[2] Chronic infections and coronary heart disease: is there a link? [J].

Danesh, J ;

Collins, R ;

Peto, R .

LANCET, 1997, 350 (9075) :430-436

[3] INFECTIONS CAUSED BY CHLAMYDIA-PNEUMONIAE STRAIN TWAR [J].

GRAYSTON, JT .

CLINICAL INFECTIOUS DISEASES, 1992, 15 (05) :757-763

[4]

Gupta S, 1997, CIRCULATION, V96, P404

[5] Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS pilot study [J].

Gurfinkel, E ;

Bozovich, G ;

Daroca, A ;

Beck, E ;

Mautner, B .

LANCET, 1997, 350 (9075) :404-407

[6] ANTIMICROBIAL SUSCEPTIBILITY AND THERAPY OF INFECTIONS CAUSED BY CHLAMYDIA-PNEUMONIAE [J].

HAMMERSCHLAG, MR .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (09) :1873-1878

[7] Isolation of Chlamydia pneumoniae from a carotid endarterectomy specimen [J].

Jackson, LA ;

Campbell, LA ;

Kuo, CC ;

Rodriguez, DI ;

Lee, A ;

Grayston, JT .

JOURNAL OF INFECTIOUS DISEASES, 1997, 176 (01) :292-295

[8]

JONES RB, 1983, REV INFECT DIS, V5, P556

[9] INVITRO DRUG SUSCEPTIBILITY OF CHLAMYDIA SP STRAIN-TWAR [J].

KUO, CC ;

GRAYSTON, JT .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (02) :257-258

[10] CHLAMYDIA-PNEUMONIAE (TWAR) IN CORONARY-ARTERIES OF YOUNG-ADULTS (15-34 YEARS OLD) [J].

KUO, CC ;

GRAYSTON, JT ;

CAMPBELL, LA ;

GOO, YA ;

WISSLER, RW ;

BENDITT, EP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (15) :6911-6914

← 1 2 →