Functional outcomes of anemia in older adults

被引：35

作者：

Chaves, Paulo H. M. ^{[1
,2
,3
]}

机构：

[1] Johns Hopkins Univ, Dept Med, Div Geriatr Med & Gerontol, Ctr Aging & Hlth, Baltimore, MD USA

[2] Johns Hopkins Univ, Dept Epidemiol, Div Geriatr Med & Gerontol, Ctr Aging & Hlth, Baltimore, MD USA

[3] Univ Estado Rio De Janeiro, Ctr Studies Aging & Care Elderly, Rio De Janeiro, Brazil

来源：

SEMINARS IN HEMATOLOGY | 2008年 / 45卷 / 04期

关键词：

D O I：

10.1053/j.seminhematol.2008.06.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Observational studies have consistently documented independent, strong associations of anemia-even if not severe-with major adverse functional outcomes in older adults. In this chapter, recent epidemiologic evidence linking mild anemia with decline in physical and cognitive function, frailty, and disability in community-dwelling older adults is reviewed. Altogether, these biologically plausible associations provide empirical, though not conclusive, support for the notion of mild anemia as a cause of adverse functional outcomes in older adults. Randomized clinical trial data assessing the impact of anemia correction on functional outcomes are lacking at this time.

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收藏

页码：255 / 260

页数：6

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