Evolutionary analyses of the human genome

被引：307

作者：

Li, WH ^{[1
]}

Gu, ZL ^{[1
]}

Wang, HD ^{[1
]}

Nekrutenko, A ^{[1
]}

机构：

[1] Univ Chicago, Chicago, IL 60637 USA

来源：

NATURE | 2001年 / 409卷 / 6822期

关键词：

D O I：

10.1038/35057039

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The completion of the human genome will greatly accelerate the development of a new branch of science - evolutionary genomics. We can now directly address important questions about the evolutionary history of human genes and their regulatory sequences. Computational analyses of the human genome will reveal the number of genes and repetitive elements, the extent of gene duplication and compositional heterogeneity in the human genome, and the extent of domain shuffling and domain sharing among proteins. Here we present some first glimpses of these features.

引用

页码：847 / 849

页数：3

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