Chemical modifications of AFM tips for the study of molecular recognition events

被引：93

作者：

Barattin, Regis ^{[2
]}

Voyer, Normand ^{[1
]}

机构：

[1] Univ Laval, Fac Sci & Genie, Dept Chim, Ctr Rech Fonct Struct & Ingn Prot, Quebec City, PQ G1K 7P4, Canada

[2] CEA, LETI, Lab Fonctionnalisat & Chim Microsyst, F-38054 Grenoble 9, France

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 13期

关键词：

D O I：

10.1039/b614328h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The use of AFM to study molecular recognition events at an incredible level of sensitivity is currently a very active field of research. In order to get information at the single molecule level, it is mandatory to modify in a precise manner the AFM tip to anchor either ligand or receptor molecules. In the following lines, we review the achievements in tip modi. cations and illustrate the scope and limitations of the different strategies that have been reported.

引用

页码：1513 / 1532

页数：20

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