GeneTrack - a genomic data processing and visualization framework

被引:76
作者
Albert, Istvan [1 ,2 ,3 ]
Wachi, Shinichiro [2 ,3 ]
Jiang, Cizhong [2 ,3 ]
Pugh, Franklin [2 ,3 ]
机构
[1] Penn State Univ, Huck Inst Life Sci, University Pk, PA 16802 USA
[2] Penn State Univ, Ctr Comparat Genom & Bioinformat, Ctr Gene Regulat, University Pk, PA 16802 USA
[3] Penn State Univ, Dept Biochem & Mol Biol, University Pk, PA 16802 USA
关键词
D O I
10.1093/bioinformatics/btn119
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: High-throughput ChIP-chip and ChIP-seq methodologies generate sufficiently large data sets that analysis poses significant informatics challenges, particularly for research groups with modest computational support. To address this challenge, we devised a software platform for storing, analyzing and visualizing high resolution genome-wide binding data. GeneTrack automates several steps of a typical data processing pipeline, including smoothing and peak detection, and facilitates dissemination of the results via the web. Our software is freely available via the Google Project Hosting environment at http://genetrack.googlecode.com.
引用
收藏
页码:1305 / 1306
页数:2
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