Ciprofloxacin-induced acute generalized exanthematous pustulosis mimicking bullous drug eruption confirmed by a positive patch test

被引：28

作者：

Häusermann, P ^{[1
]}

Scherer, K ^{[1
]}

Weber, M ^{[1
]}

Bircher, AJ ^{[1
]}

机构：

[1] Univ Basel Hosp, Dept Dermatol, Allergy Unit, CH-4031 Basel, Switzerland

来源：

DERMATOLOGY | 2005年 / 211卷 / 03期

关键词：

acute generalized exanthematous pustulosis; ciprofloxacin; quinolone; patch test;

D O I：

10.1159/000087024

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report the case of an 80-year-old woman presenting with ciprofloxacin-induced acute generalized exanthematous pustulosis (AGEP) confirmed by a positive patch test. Cutaneous morphology, course and histological findings were consistent with a definite diagnosis according to the AGEP validation score of the EuroSCAR study group. We point to the rarity of quinolone-induced AGEP and discuss immunological mechanisms, the value of in vivo and in vitro tests as well as the main differential diagnosis. Furthermore, we highlight in this particular case the challenging differentiation from bullous drug eruption.

引用

页码：277 / 280

页数：4

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