Electrostatic edge instability of lipid membranes

被引：48

作者：

Betterton, MD ^{[1
]}

Brenner, MP

机构：

[1] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA

[2] MIT, Dept Math, Cambridge, MA 02139 USA

来源：

PHYSICAL REVIEW LETTERS | 1999年 / 82卷 / 07期

关键词：

D O I：

10.1103/PhysRevLett.82.1598

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

This paper considers the effect of electrostatics on the stability of a charged membrane. We show that at low ionic strength and high surface charge density, repulsion between charges on the membrane renders it unstable to the formation of holes. A free straight edge is unstable to modulations with wavelength longer than the Debye screening length. Hence, at low ionic strength membranes will disintegrate into vesicles. We use these results to interpret stable holes in red blood cell ghosts.[S0031-9007(98)08370-7].

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页码：1598 / 1601

页数：4

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