Effects on tyrosinase activity by the extracts of Ganoderma lucidum and related mushrooms

被引：62

作者：

Chien, Chih-Ching ^{[1
]}

Tsai, Mei-Ling ^{[1
,2
]}

Chen, Chin-Chu ^{[2
]}

Chang, Shing-Jyh ^{[3
,4
]}

Tseng, Ching-Hui ^{[5
]}

机构：

[1] Yuan Ze univ, Grad Sch Biotechnol & Bioengn, Chungli 320, Taiwan

[2] Grape King Inc, Ctr Biotechnol, Chungli 320, Taiwan

[3] Hsinchu Mackay Mem Hosp, Dept Obstet & Gynecol, Hsinchu 300, Taiwan

[4] Natl Tsing Hua Univ, Coll Life Sci, Hsinchu 300, Taiwan

[5] Ching Hui Chinese Med Clin, Hsinchu 300, Taiwan

来源：

MYCOPATHOLOGIA | 2008年 / 166卷 / 02期

关键词：

Ganoderma lucidum; Lingzhi; medicinal mushroom; Tyrosinase;

D O I：

10.1007/s11046-008-9128-x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

The inhibitory effects on tyrosinase activity by extracts of several mushrooms belonging to Basidiomycetes were evaluated. Among the tested mushrooms (Ganoderma lucidum, Antrodia camphorata, Agaricus brasiliensis, and Cordyceps militaris), G. lucidum exhibited significant inhibition of tyrosinase activity (IC(50) value 0.32 mg/ml), compared to those prepared from other Basidiomycetes. Tyrosinase inhibitors are effective components of skin-lightening compounds and other cosmetics; currently many of the facial mask cosmetics in the market contain Ganoderma extracts in their ingredients. The finding that mushroom extracts contain tyrosinase activity inhibition will contribute to better understanding of how their 'Cyhealing' properties in various Chinese traditional herbal on skin care products.

引用

页码：117 / 120

页数：4

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