Re-evaluation of mammary stem cell biology based on in vivo transplantation

被引:43
作者
Smith, Gilbert H. [1 ]
Medina, Daniel [2 ]
机构
[1] NIH, Mammary Stem Cell Biol Sect, Mammary Biol & Tumorigenesis Lab, CCR,NCI, Bethesda, MD 20892 USA
[2] Baylor Coll Med, Dept Mol & Cellular Biol, Houston, TX 77030 USA
来源
BREAST CANCER RESEARCH | 2008年 / 10卷 / 01期
关键词
D O I
10.1186/bcr1856
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Over nearly half a century, transplantation methods have been employed to regenerate the mammary gland in vivo. Recent highly cited reports claim to have demonstrated the regeneration of an entire functional mammary gland from a single mammary epithelial cell. Nevertheless, re- examination of the literature on the transplantation biology of mammary gland regeneration reveals that a complex, combinatorial interaction between variously differentiated mammary epithelial cells and the mammary fat pad stroma is indispensable to this process. In the present article, these issues are reviewed and discussed to provide a greater understanding of the complexity of these multiplex interactions.
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页数:6
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共 37 条
[1]   Alveolar progenitor in mouse mammary cells develop glands independent of pregnancy and lactation [J].
Booth, Brian W. ;
Boulanger, Corinne A. ;
Smith, Gilbert H. .
JOURNAL OF CELLULAR PHYSIOLOGY, 2007, 212 (03) :729-736
[2]   Estrogen receptor-α and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands [J].
Booth, Brian W. ;
Smith, Gilbert H. .
BREAST CANCER RESEARCH, 2006, 8 (04)
[3]   Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-β1 expression [J].
Boulanger, CA ;
Wagner, KU ;
Smith, GH .
ONCOGENE, 2005, 24 (04) :552-560
[4]   A paracrine role for the epithelial progesterone receptor in mammary gland development [J].
Brisken, C ;
Park, S ;
Vass, T ;
Lydon, JP ;
O'Malley, BW ;
Weinberg, RA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) :5076-5081
[5]   MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways [J].
Callahan, R ;
Smith, GH .
ONCOGENE, 2000, 19 (08) :992-1001
[6]   Amphiregulin is an essential mediator of estrogen receptor α function in mammary gland development [J].
Ciarloni, Laura ;
Mallepell, Sonia ;
Brisken, Cathrin .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (13) :5455-5460
[7]  
DANIEL CW, 1975, FED PROC, V34, P64
[8]   INFLUENCE OF MAMMOGENIC HORMONES ON SERIALLY TRANSPLANTED MOUSE MAMMARY GLAND [J].
DANIEL, CW ;
YOUNG, LJT ;
MEDINA, D ;
DEOME, KB .
EXPERIMENTAL GERONTOLOGY, 1971, 6 (01) :95-&
[9]   GROWTH OF MOUSE MAMMARY GLANDS IN VIVO AFTER MONOLAYER CULTURE [J].
DANIEL, CW ;
DEOME, KB .
SCIENCE, 1965, 149 (3684) :634-&
[10]   INFLUENCE OF CELL DIVISION ON AN AGING PROCESS - LIFE SPAN OF MOUSE MAMMARY EPITHELIUM DURING SERIAL PROPAGATION IN-VIVO [J].
DANIEL, CW ;
YOUNG, LJT .
EXPERIMENTAL CELL RESEARCH, 1971, 65 (01) :27-&