Quantitative analysis on tongue inspection in traditional Chinese medicine using optical coherence tomography

被引:28
作者
Dong, Haixin [1 ]
Guo, Zhouyi [1 ]
Zeng, Changchun [1 ]
Zhong, Huiqing [1 ]
He, Yonghong [2 ]
Wang, Ruikang K. [3 ]
Liu, Songhao [1 ]
机构
[1] S China Normal Univ, Minist Educ, Key Lab Laser Life Sci, Lab Photon Tradit Chinese Med, Guangzhou 510631, Peoples R China
[2] Tsinghua Univ, Grad Sch Shenzhen, Shenzhen 518055, Peoples R China
[3] Oregon Hlth & Sci Univ, Dept Biomed Engn, Beaverton, OR 97006 USA
基金
中国国家自然科学基金;
关键词
optical coherence tomography; tongue inspection; tongue coating; microstructure; moisture degree;
D O I
10.1117/1.2870175
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Tongue inspection (TI) is an important and unique diagnostic method in traditional Chinese medicine (TCM), because significant connections between various viscerae diseases and abnormalities in the tongue have been verified. In TCM, TI is simple and non invasive, but in clinical applications, TI is subjectively based on the experience and technique of physicians. To avoid this problem, optical coherence tomography (OCT) imaging is introduced here for TI. We study OCT imaging in rats in vivo from chronic gastritis group (model) and normal group (control) and quantitatively analyze the relative parameters, such as the thickness and the moisture degree of TI. Our results show that OCT images properly demonstrate the thickness of the tongue coating and the moisture degree of the tongue in both groups, and the thickness is increased in the model group from that in the normal group, while the moisture degree decreases. As a result, OCT technology has the potential to provide physicians with an objective diagnostic standard for visual TI in TCM clinical practice and research. (C) 2008 Society of Photo-Optical Instrumentation Engineers.
引用
收藏
页数:6
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