Improved synthesis of 3-spiro indolines in dry media under microwave irradiation

被引：28

作者：

Dandia, A ^{[1
]}

Sachdeva, H ^{[1
]}

Singh, R ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 12期

关键词：

D O I：

10.1081/SCC-100104339

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, one-pot synthesis of novel spiro [indole-dipyrrolopyridines] (8) was achieved under microwave irradiation by the interaction of spiro [indole-dipyrrolopyrans] (3) with ammonium acetate (7) in the presence of acetic acid. Spiro [indole-dipyrrolopyrans] (3) were synthesized "in situ" by the reaction of indole-2,3-diones (1) and 2-pyrrolidone (2) in 1:2 molar ratio by microwave induced techniques for the first time. Comparative studies have been made between (a) microwave irradiation of (i) neat reaction of reactants in the absence of any solvent or catalyst (ii) reaction in presence of o-dichlorobenzene and (b) classical heating.

引用

页码：1879 / 1892

页数：14

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