Relating biochemistry and function in the myosin superfamily

被引：202

作者：

De La Cruz, EM

Ostap, EM

机构：

[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA

[2] Univ Penn, Sch Med, Penn Muscle Inst, Philadelphia, PA 19104 USA

[3] Univ Penn, Sch Med, Dept Physiol, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2004年 / 16卷 / 01期

关键词：

D O I：

10.1016/j.ceb.2003.11.011

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

All characterized myosins share a common ATPase mechanism. However, detailed kinetic analyses suggest that modulation of the rate and equilibrium constants that define the ATPase cycle confers specific properties to these motor proteins, suiting them to specific physiological tasks. Understanding the kinetic mechanisms allows potential cellular functions of the different myosin classes and isoforms to be better defined.

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页码：61 / 67

页数：7

相关论文

共 60 条

[1] Myosin V is a left-handed spiral motor on the right-handed actin helix [J].

Ali, MY ;

Uemura, S ;

Adachi, K ;

Itoh, H ;

Kinosita, K ;

Ishiwata, S .

NATURE STRUCTURAL BIOLOGY, 2002, 9 (06) :464-467

[2]

[Anonymous], 2001, MECH MOTOR PROTEINS

[3] A millennial myosin census [J].

Berg, JS ;

Powell, BC ;

Cheney, RE .

MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (04) :780-794

[4] The prepower stroke conformation of myosin V [J].

Burgess, S ;

Walker, M ;

Wang, F ;

Seller, JR ;

White, HD ;

Knight, PJ ;

Trinick, J .

JOURNAL OF CELL BIOLOGY, 2002, 159 (06) :983-991

[5] Myosin VI, an actin motor for membrane traffic and cell migration [J].

Buss, F ;

Luzio, JP ;

Kendrick-Jones, J .

TRAFFIC, 2002, 3 (12) :851-858

[6] Transient kinetic analysis of the 130-kDa myosin I (MYR-1 gene product) from rat liver - A myosin I designed for maintenance of tension? [J].

Coluccio, LR ;

Geeves, MA .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (31) :21575-21580

[7] Actin and light chain isoform dependence of myosin V kinetics [J].

De la Cruz, EM ;

Wells, AL ;

Sweeney, HL ;

Ostap, EM .

BIOCHEMISTRY, 2000, 39 (46) :14196-14202

[8] The kinetic mechanism of myosin V [J].

De La Cruz, EM ;

Wells, AL ;

Rosenfeld, SS ;

Ostap, EM ;

Sweeney, HL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (24) :13726-13731

[9] Kinetic mechanism and regulation of myosin VI [J].

De la Cruz, EM ;

Ostap, EM ;

Sweeney, HL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (34) :32373-32381

[10] RELATION OF MUSCLE BIOCHEMISTRY TO MUSCLE PHYSIOLOGY [J].

EISENBERG, E ;

GREENE, LE .

ANNUAL REVIEW OF PHYSIOLOGY, 1980, 42 :293-309

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