The re-emergence of American visceral leishmaniasis in an old focus in Venezuela:: Present situation of human and canine infections

被引:23
作者
Delgado, O
Feliciangeli, MD
Gomez, B
Alvarado, J
García, L
Bello, C
机构
[1] Univ Carabobo, Fac Ciencias Salud, BIOMED, Maracay, Venezuela
[2] Cent Univ Venezuela, Inst Trop Med, Caracas, Venezuela
[3] Cent Univ Venezuela, Inst Biomed, Maracay, Venezuela
[4] Inst Invest Vet, Maracay, Venezuela
[5] Escuela Malariol & Saneamiento Ambiental Dr Arnol, Maracay, Venezuela
关键词
AVL; human visceral leishmaniosis; canine visceral leishmaniasis; re-emergence; Venezuela;
D O I
10.1051/parasite/1998054317
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The report of a new autochthonous case of human American Visceral Leishmaniasis (AVL) in 1992 in the village of Guayabita, Aragua State. Venezuela (10 degrees 16'N, 67 degrees 28'W; 500 m asl), led us to undertake on epidemiological study in this locality. A demographic survey was conducted using a structured questionnaire in which data was collected regarding sex, age, occupation, length of residence in the area and migratory history. A leishmanin skin test (LST) was applied and samples of venous blood for counter immunoelectrophoresis (CIEP) and immunofluorescent antibodies (IFAT) tests were drawn. The prevalence of positive LST was 11.4 %. The positivity was highest among males and increased with age. Young males seemed to be more exposed to infection than females. Since occupation per se did not seem to account for this association, it may be explained as a gender-associated behavior, leading to different degrees of exposure to sand flies. The canine population was also screened for leishmanial infection. One dog was shown to be parasitologically infected with leishmania sp. Four out of 71 dogs (5.6 %) were positive for FG, CIEP, IFAT and Western Blot and 11 (15.5 %) were positive for CIEP. These results suggest that after almost 30 years of epidemiological silence, American visceral leishmaniasis has reemerged in this focus.
引用
收藏
页码:317 / 323
页数:7
相关论文
共 34 条
[1]   Urban visceral leishmaniasis in Venezuela [J].
Aguilar, CM ;
Fernandez, E ;
Fernandez, R ;
Cannova, DC ;
Ferrer, E ;
Cabrera, Z ;
Souza, WJS ;
Coutinho, SG .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1998, 93 (01) :15-16
[2]   VISCERAL LEISHMANIASIS IN ETHIOPIA .1. CROSS-SECTIONAL LEISHMANIN SKIN-TEST IN AN ENDEMIC LOCALITY [J].
ALI, A ;
ASHFORD, RW .
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 1993, 87 (02) :157-161
[3]  
AMARAL A D, 1961, Gac Med Caracas, V70, P389
[4]  
AMARAL A. D. F., 1961, REV INST MED TROP SAO PAULO, V3, P91
[5]  
AMARAL A. D. F., 1961, Revista de Sanidad y Asistencia Social, V26, P350
[6]  
AMARAL A. D. F., 1961, Folia Clinica et Biologica, V30, P14
[7]   The reemergence of visceral leishmaniasis in Brazil [J].
Arias, JR ;
Monteiro, PS ;
Zicker, F .
EMERGING INFECTIOUS DISEASES, 1996, 2 (02) :145-146
[8]  
ASHFORD RW, 1985, HUMAN PARASITIC DISE, V1, P377
[9]   A PROSPECTIVE-STUDY OF VISCERAL LEISHMANIASIS IN AN ENDEMIC AREA OF BRAZIL [J].
BADARO, R ;
JONES, TC ;
LORENCO, R ;
CERF, BJ ;
SAMPAIO, D ;
CARVALHO, EM ;
ROCHA, H ;
TEIXEIRA, R ;
JOHNSON, WD .
JOURNAL OF INFECTIOUS DISEASES, 1986, 154 (04) :639-649
[10]   STUDIES ON IMMUNOLOGY AND SEROLOGY OF LEISHMANIASIS .9. SEROLOGICAL INVESTIGATION OF PARASITES OF INDIAN KALA-AZAR AND INDIAN POST-KALAAZAR DERMAL LEISHMANIASIS [J].
BRAY, RS ;
ASHFORD, RW ;
MUKHERJEE, AM ;
SENGUPTA, PC .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1973, 67 (01) :125-129