Integrating research into routine service delivery in an antiretroviral treatment programme: lessons learnt from a cluster randomized trial comparing strategies of HIV care in Jinja, Uganda

被引：15

作者：

Jaffar, Shabbar ^{[1
]}

Amuron, Barbara ^{[2
]}

Birungi, Josephine ^{[3
]}

Namara, Geoffrey ^{[2
]}

Nabiryo, Christine ^{[3
]}

Coutinho, Alex ^{[3
]}

Grosskurth, Heiner ^{[2
]}

机构：

[1] Univ London London Sch Hyg & Trop Med, Dept Epidemiol & Populat Hlth, London WC1E 7HT, England

[2] MRC UVRI Uganda Res Unit AIDS, Entebbe, Uganda

[3] AIDS Support Org, Kampala, Uganda

来源：

TROPICAL MEDICINE & INTERNATIONAL HEALTH | 2008年 / 13卷 / 06期

基金：

英国医学研究理事会;

关键词：

HIV/AIDS; antiretroviral; Uganda; effectiveness; health services research;

D O I：

10.1111/j.1365-3156.2008.02068.x

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Trials integrated into normal health service delivery are designed to evaluate the effectiveness of interventions under real-life conditions. However, integrating research into service delivery creates many operational challenges and raises ethical dilemmas. Here we discuss the operational and ethical issues arising from such trials using the example of a cluster randomized trial evaluating two strategies of ART delivery in Jinja, south-east Uganda.

引用

页码：795 / 800

页数：6

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