Treating COVID-19-Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics

被引：329

作者：

Kalil, Andre C. ^{[1
]}

机构：

[1] Univ Nebraska, Med Ctr, Dept Internal Med, Div Infect Dis, Omaha, NE USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2020年 / 323卷 / 19期

关键词：

CORTICOSTEROID TREATMENT;

D O I：

10.1001/jama.2020.4742

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

This Viewpoint uses the absence of known effective treatment for Ebola virus disease to emphasize the costs of off-label and compassionate drug use during an infectious disease outbreak and the importance of establishing the efficacy and safety of promising drug leads in randomized trials to inform their clinical use.

引用

页码：1897 / 1898

页数：2

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