RETRACTED: Efficacy of thoracic epidural analgesia following laparoscopic cholecystectomy (Retracted article. See vol. 30, pg. 262, 2013)

This study was undertaken to determine whether epidural analgesia has any benefit for post-operative pain relief in patients undergoing laparoscopic cholecystectomy. Patients were randomly assigned to receive post-operative epidural analgesia with a morphine-bupivacaine combination (Group A, n=22) or placebo (saline) (Group B, n=22). The same standard general anaesthetic technique, which consists of nitrous oxide and isoflurane in oxygen was used. Analgesia was assessed using visual analogue pain scores (0-10 cm). The evaluation was carried out 24 and 48 h post-operatively. At 24 h after anaesthesia, pain scores in Group A (2.3+/-1.2) were lower than those in Group B (4.4+/-1.5) (P<0.05). However, at 48 h post-operatively, no difference in scores was observed between the two groups. in conclusion, epidural analgesia with a morphine-bupivacaine combination improves pain relief during the first 24 h following laparoscopic cholecystectomy.