Evaluation of antipyretic potential of Cleome viscosa Linn. (Capparidaceae) extract in rats

被引：39

作者：

Devi, BP ^{[1
]}

Boominathan, R ^{[1
]}

Mandal, SC ^{[1
]}

机构：

[1] Jadavpur Univ, Fac Engn & Technol, Dept Pharmaceut Technol, Div Pharmacognosy, Kolkata 700032, W Bengal, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2003年 / 87卷 / 01期

关键词：

Cleome viscosa; entire plant; methanol extract; CVME; anti-pyretic;

D O I：

10.1016/S0378-8741(03)00099-0

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

The antipyretic activity of a methanol extract of Cleome viscosa Linn. (CVME) was investigated for its, potential on normal body temperature and yeast-induced pyrexia in albino rats. The CVME, at doses of 200, 300, and 400 mg/kg BW p.o., showed significant reduction in normal body temperature and yeast-provoked elevated temperature in a dose-dependent manner. The effect also extended upto 5 h after the drug administration. The anti-pyretic effect of CVME was comparable to that of paracetamol (150 mg/kg p.o.,), a standard anti-pyretic agent. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：11 / 13

页数：3