OBESITY New life for antidiabetic drugs

被引：25

作者：

Houtkooper, Riekelt H. ^{[1
]}

Auwerx, Johan ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Lab Integrat & Syst Physiol, CH-1015 Lausanne, Switzerland

来源：

NATURE | 2010年 / 466卷 / 7305期

基金：

欧洲研究理事会;

关键词：

GAMMA; CDK5; FAT;

D O I：

10.1038/466443a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

Antidiabetic drugs that activate the protein PPARγ had a bright start but soon lost their appeal because of undesirable side effects. Subtle modifications may once again make them suitable for treating diabetes.

引用

页码：443 / 444

页数：2

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