An improved linkage map of rat Chromosome 3 with three mapping panels

被引：7

作者：

Dene, H ^{[1
]}

Choi, CR

Cicila, GT

Garrett, MR

Dukhanina, OI

Bihoreau, MT

Hoebee, B

Rapp, JP

机构：

[1] Med Coll Ohio, Dept Physiol & Mol Med, Toledo, OH 43614 USA

[2] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England

[3] Natl Inst Publ Hlth & Environm, Hlth Effects Res Lab, NL-3720 BA Bilthoven, Netherlands

来源：

MAMMALIAN GENOME | 1998年 / 9卷 / 07期

基金：

英国惠康基金;

关键词：

D O I：

10.1007/s003359900811

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Our purposes were to develop an improved linkage map for rat Chromosome 3 and to develop new markers polymorphic between Dahl salt-sensitive (S) and Dahl salt-resistant (R) rats. The linkage mapping panel consisted of three F-2 populations totaling 359 rats. Twenty-five new markers were developed and placed on the linkage map. About half of these markers (13) were polymorphic between S and R rats. The final map spans 124.7 centiMorgans (cM) and includes 64 markers. The average distance between adjacent markers is 1.9 cM, and the largest separation is 10.5 cM.

引用

页码：517 / 520

页数：4

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