One-pot synthesis of functionalized furamide derivatives via a three-component reaction between an amine, diketene and dibenzoylacetylene in the presence of triphenylphosphine

被引：41

作者：

Alizadeh, Abdolali ^{[1
]}

Zohreh, Nasrin ^{[1
]}

Rostamnia, Sadegh ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON | 2007年 / 63卷 / 34期

关键词：

amine; diketene; dibenzoylacetylene; triphenylphosphine; furamide; multicomponent reaction;

D O I：

10.1016/j.tet.2007.06.021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An effective route to functionalized furamide derivatives is described. This involves reaction of N-alkyl-3-oxobutanamides, derived from the addition of amines to the diketene, and dibenzoylacetylene in the presence of triphenylphosphoine. The reactive 1:1 intermediate obtained from the addition of triphenylphosphine to dibenzoylacetylene was trapped by OH-acids such as N-alkyl-3-oxobutanamide to produce functionalized furamide derivatives. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：8083 / 8087

页数：5

共 68 条

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