Early upregulation of T cell IL-10 production plays an important role in oral tolerance induction

被引：7

作者：

Cong, Y ^{[1
]}

Liu, C

Weaver, CT

Elson, CO

机构：

[1] Univ Alabama, Dept Med, Div Gastroenterol, Birmingham, AL 35294 USA

[2] Univ Alabama, Dept Pathol, Div Gastroenterol, Birmingham, AL 35294 USA

来源：

ORAL TOLERANCE: NEW INSIGHTS AND PROSPECTS FOR CLINICAL APPLICATION | 2004年 / 1029卷

关键词：

IL-10; production; dendritic cells; transgenic mice;

D O I：

10.1196/annals.1309.037

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Early in oral tolerance induction, IL-10-producing CD4(+) T cells were increased, and adoptive transfer of IL-10-dericient CD4(+) T cells failed induction of oral tolerance, suggesting a key role of IL-10 production in such a process.

引用

页码：319 / 320

页数：2