New perspectives on mitochondrial morphology in cell function

被引:26
作者
Brocard, JB [1 ]
Rintoul, GL [1 ]
Reynolds, IJ [1 ]
机构
[1] Univ Pittsburgh, Sch Med, Dept Pharmacol, Pittsburgh, PA 15261 USA
关键词
excitotoxicity; calcium signaling; mitochoadrial fission/fision;
D O I
10.1016/S0248-4900(03)00062-5
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mitochondria are a node of integration for intracellular signaling pathways and their morphology changes seem to be tightly associated with their function. New data show that morphology is one of the parameters involved in mitochondria's choice between promoting cell death and protecting cells against general metabolic jeopardy. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:239 / 242
页数:4
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