Neuronal potential and lineage determination by neural stem cells

被引：94

作者：

Morrison, SJ

机构：

[1] Univ Michigan, Howard Hughes Med Inst, Dept Internal Med, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Howard Hughes Med Inst, Dept Cell & Dev Biol, Ann Arbor, MI 48109 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2001年 / 13卷 / 06期

关键词：

D O I：

10.1016/S0955-0674(00)00269-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

How do neural stem cells ensure that they give rise to the right number and type of neurons at the right time? Over the past year several regulatory mechanisms have been identified, including promotion of neurogenesis by proneural bHLH genes, instruction of gliogenesis by Notch, and cell-intrinsic changes in the neurogenic capacity of stem cells in culture and in vivo.

引用

收藏

页码：666 / 672

页数：7

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