Dombrock blood group (DO): Assignment to chromosome 12p

被引：12

作者：

Eiberg, H

Mohr, J

机构：

[1] Institute of Medical Biochemistry and Genetics, Department of Genetics, Building 24.4, DK-2200 Copenhagen N

来源：

HUMAN GENETICS | 1996年 / 98卷 / 05期

关键词：

D O I：

10.1007/s004390050251

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Dombrock blood group system (DO) is a common polymorphism in Caucasians, represented by two red cell antigen alleles. In a linkage study in our family material of 832 families from the Copenhagen area, we found a strong indication of tight linkage with the two flanking DNA polymorphisms D12S358 (z = 7.66; at theta(M) = 0.001, theta(F) = 0.031) and D12S364 (z = 8.53; at theta(M) = 0.068, theta(F) = 0.031), DO is assigned to the region 12p13.2-12p12.1 by physically localised markers.

引用

页码：518 / 521

页数：4

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