Arsenic

被引:36
作者
Frumkin, H [1 ]
Thun, MJ
机构
[1] Emory Univ, Dept Environm & Occupat Hlth, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA
[2] Amer Canc Soc, Epidemiol & Surveillance Res, Atlanta, GA 30329 USA
关键词
D O I
10.3322/canjclin.51.4.254
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
The toxicity and carcinogenicity of arsenic are well known, but vexing questions remain. The current controversy over the appropriate Federal limit for arsenic in drinking water highlights some of the difficult scientific, ethical, economic, and political issues that complicate standard-setting ill occupational and environmental health. These include limitations in the scientific evidence concerning the risk at low doses, uncertainty about the appropriate mathematical models for estimating the risk at low-level exposures based on data from higher-level exposures, and controversies concerning the appropriate safety margin, level of evidence required for standard-setting, and costs of remediation.
引用
收藏
页码:254 / 262
页数:9
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