Regulation of sigL expression by the catabolite control protein CcpA involves a roadblock mechanism in Bacillus subtilis:: Potential connection between carbon and nitrogen metabolism

被引：50

作者：

Choi, SK

Saier, MH ^{[1
]}

机构：

[1] Univ Calif San Diego, Div Biol Sci, La Jolla, CA 92093 USA

[2] Korea Res Inst Biosci & Biotechnol, Genome Res Ctr, Lab Microbial Genom, Taejon 305333, South Korea

来源：

JOURNAL OF BACTERIOLOGY | 2005年 / 187卷 / 19期

关键词：

D O I：

10.1128/JB.187.19.6856-6861.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A catabolite-responsive element (CRE), a binding site for the CcpA transcription factor, was identified within the sigL structural gene encoding sigma(L) in Bacillus subtilis. We show that CcpA binds to this CRE to regulate sigL expression by a "roadblock" mechanism and that this mechanism in part accounts for catabolite repression of sigma(L)-directed levD operon expression.

引用

页码：6856 / 6861

页数：6

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