Effect of coffee oil and its unsaponifiable fraction on plasma cholesterol level in female rats

被引：3

作者：

Al-Kanhal, MA ^{[1
]}

Ahmed, F ^{[1
]}

Arif, Z ^{[1
]}

机构：

[1] King Saud Univ, Coll Appl Med Sci, Dept Community Hlth Sci, Riyadh 11433, Saudi Arabia

来源：

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION | 1999年 / 50卷 / 02期

关键词：

D O I：

10.1080/096374899101283

中图分类号：

TS2 [食品工业];

学科分类号：

0832 [食品科学与工程];

摘要：

The present study was conducted to identify the cholesterol-raising factor in coffee oil besides the other two well-known diterpenes, cafestol and kahweol. Female rats fed coffee oil for 4 weeks showed significantly higher level of plasma cholesterol (P < 0.01) and triacylglycerols (P < 0.01). Feeding unsaponifiable lipids of coffee oil caused significant decrease in plasma cholesterol; however, increase in triacylglycerol was observed. Rats given beta-sitosterol showed increase in plasma triacylglecerol and decrease in cholesterol levels, an effect similar to that observed with unsaponifiable lipids. beta-sitosterol is the major constituent of unsaponifiable lipids of the coffee oil. These results show that cafestol and kahweol diterpene alcohols are not the only cholesterol-raising factors in coffee oil.

引用

页码：99 / 103

页数：5

共 33 条

[1]

Lipid analysis of Coffea arabica Linn beans and their possible hypercholesterolemic effects [J].

AlKanhal, MA .

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, 1997, 48 (02) :135-139

[2]

ALKANHAL MA, 1994, MED SCI RES, V22, P853

[3]

THE EFFECT ON SERUM-CHOLESTEROL LEVELS OF COFFEE BREWED BY FILTERING OR BOILING [J].

BAK, AAA ;

GROBBEE, DE .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (21) :1432-1437

[4]

COFFEE AND CHOLESTEROL - IS IT ALL IN THE BREWING - THE TROMSO STUDY [J].

BONAA, K ;

ARNESEN, E ;

THELLE, DS ;

FORDE, OH .

BRITISH MEDICAL JOURNAL, 1988, 297 (6656) :1103-1104

[5]

THE ROLE OF FATTY-ACID SATURATION ON PLASMA-LIPIDS, LIPOPROTEINS, AND APOLIPOPROTEINS .2. THE PLASMA TOTAL AND LOW-DENSITY-LIPOPROTEIN CHOLESTEROL RESPONSE OF INDIVIDUAL FATTY-ACIDS [J].

DERR, J ;

KRISETHERTON, PM ;

PEARSON, TA ;

SELIGSON, FH .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1993, 42 (01) :130-134

[6]

FOLCH J, 1957, J BIOL CHEM, V226, P497

[7]

THE TROMSO HEART-STUDY - COFFEE CONSUMPTION AND SERUM-LIPID CONCENTRATIONS IN MEN WITH HYPERCHOLESTEROLEMIA - A RANDOMIZED INTERVENTION STUDY [J].

FORDE, OH ;

KNUTSEN, SF ;

ARNESEN, E ;

THELLE, DS .

BRITISH MEDICAL JOURNAL, 1985, 290 (6472) :893-895

[8]

THE EFFECT OF FILTERED-COFFEE CONSUMPTION ON PLASMA-LIPID LEVELS - RESULTS OF A RANDOMIZED CLINICAL-TRIAL [J].

FRIED, RE ;

LEVINE, DM ;

KWITEROVICH, PO ;

DIAMOND, EL ;

WILDER, LB ;

MOY, TF ;

PEARSON, TA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 267 (06) :811-815

[9]

COFFEE, CAFFEINE, AND CARDIOVASCULAR-DISEASE IN MEN [J].

GROBBEE, DE ;

RIMM, EB ;

GIOVANNUCCI, E ;

COLDITZ, G ;

STAMPFER, M ;

WILLETT, W .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (15) :1026-1032

[10]

GRUNDY SM, 1990, J LIPID RES, V31, P1149

← 1 2 3 4 →