Tandem deprotection-coupling of Nα-Alloc-amino acids by use of ternary systems Pd cat./PhSiH3/carboxy-activated amino acid

被引：22

作者：

Thieriet, N ^{[1
]}

Gomez-Martinez, P ^{[1
]}

Guibé, F ^{[1
]}

机构：

[1] Univ Paris Sud, Inst Chim Mol Orsay, Lab React Organ Select, CNRS, F-91405 Orsay, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 13期

关键词：

acylation; palladium; peptide; protecting groups;

D O I：

10.1016/S0040-4039(99)00240-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-alpha-allyloxycarbonyl derivatives of amino acids undergo smooth coupling with various carboxy-activated partners when treated with phenylsilane (PhSiH3) in the presence of catalytic amounts of tetrakis-(triphenylphosphine) palladium. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2505 / 2508

页数：4

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