A gene expression bar code for microarray data

被引:97
作者
Zilliox, Michael J.
Irizarry, Rafael A.
机构
[1] Johns Hopkins Blomberg Sch Publ Hlth, Dept Biostat, Baltimore, MD 21205 USA
[2] Johns Hopkins Blomberg Sch Publ Hlth, W Harry Feinstone Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA
关键词
D O I
10.1038/NMETH1102
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The ability to measure genome-wide expression holds great promise for characterizing cells and distinguishing diseased from normal tissues. Thus far, microarray technology has been useful only for measuring relative expression between two or more samples, which has handicapped its ability to classify tissue types. Here we present a method that can successfully predict tissue type based on data from a single hybridization.
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收藏
页码:911 / 913
页数:3
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