Transplantation rate of the blood group B waiting list is increased by using A2 and A2B kidneys

被引:21
作者
Bryan, CF
Shield, CF
Nelson, PW
Pierce, GE
Ross, G
Luger, AM
Warady, BA
Helling, TS
Aeder, MI
Martinez, J
Hughes, TR
Beck, ML
Harrell, KM
机构
[1] Midwest Organ Bank Inc, Westwood, KS 66205 USA
[2] Via Christi St Francis Reg Med Ctr, Wichita, KS USA
[3] Univ Missouri, Kansas City, MO 64110 USA
[4] Univ Kansas, Med Ctr, Kansas City, MO USA
[5] Univ Missouri, Hosp & Clin, Columbia, MO USA
[6] Childrens Mercy Hosp, Kansas City, MO 64108 USA
[7] Res Med Ctr, Kansas City, MO USA
[8] St Johns Reg Med Ctr, Joplin, MO USA
[9] Midwest Organ Bank Inc, Wichita, KS USA
[10] Community Blood Ctr Greater Kansas City, Kansas City, MO USA
[11] Univ Missouri, Kansas City, MO 64110 USA
关键词
D O I
10.1097/00007890-199812270-00025
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. We have increased the transplantation rate for blood group B cadaveric waiting list candidates by transplanting them with A(2) and A(2)B kidneys. Methods. Since 1991, five of the seven renal transplant programs in our organ procurement organization service area have preferentially transplanted blood group A(2) and A(2)B cadaveric kidneys to B blood group waiting list candidates with histories of low anti-A isoagglutinin titers. Results. Between 1991 and 1997, these five centers performed transplantations on 71 patients from the B cadaveric: waiting list. Of those 71 patients, 29% (21 of 71) underwent transplantation with either A(2) (n = 18) or A(2)B (n = 3) cadaveric kidneys. In 1997 alone, 48% (11 of 23) of the B patient transplant recipients received A,or A(2)B kidneys. Conclusions. Transplantation of A(2) and A(2)B kidneys into B waiting list patients has successfully increased access of B patients to kidneys. Such an allocation algorithm implemented nationally may similarly increase the transplantation rate of B waiting list candidates.
引用
收藏
页码:1714 / 1717
页数:4
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