In vitro study of the potential role of quinupristin/dalfopristin in the treatment of catheter-related staphylococcal infections

被引：6

作者：

Garcia, R

Raad, I

机构：

[1] Univ. Texas M. D. Anderson Cancer C., Department of Medical Specialties, Section of Infectious Diseases, Houston, TX 77030

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1996年 / 15卷 / 12期

关键词：

D O I：

10.1007/BF01690511

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The susceptibility of clinical isolates of methicillin-susceptible and -resistant staphylococci from cancer patients with central venous catheter bacteremia to quinupristin/dalfopristin, a semisynthetic streptogramin, was determined in vitro. Susceptibility of these isolates to nine other antistaphylococcal antibiotics was also determined for comparison. A total of 197 staphylococcal strains were tested from 1983 to 1992. Quinupristin/dalfopristin was bactericidal against all isolates, independent of their resistance to methicillin. Its activity was similar to that of vancomycin but superior to that of teicoplanin. Quinupristin/dalfopristin may prove to be an important addition to our armamentarium against catheter-related staphylococcal infections.

引用

页码：933 / 936

页数：4

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