Metalation of 3-trimethylsilyl propargyl chloride:: A stereoselective access to trans-propargylic oxiranes.

被引：12

作者：

Chemla, F ^{[1
]}

Bernard, N ^{[1
]}

Normant, JF ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Organo Elements, F-75252 Paris 05, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(98)80023-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The metalation of 3-trimethylsilyl-1-chloroprop-2-yne and the subsequent reaction with aldehydes affords stereospecifically anti-chlorohydrins which give after treatment with potassium fluoride and NaOH propargylic epoxides with good to excellent yields. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：75 / 78

页数：4

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