Efficacy, safety, and outcome of atrial fibrillation ablation in septuagenarians

被引：77

作者：

Corrado, Andrea ^{[2
,3
]}

Patel, Dimpi ^{[2
]}

Riedlbauchova, Lucie ^{[2
]}

Fahmy, Tamer S. ^{[2
]}

Themistoclakis, Sakis ^{[3
]}

Bonso, Aldo ^{[3
]}

Rossillo, Antonio ^{[3
]}

Hao, Steven ^{[4
]}

Schweikert, Robert A. ^{[2
]}

Cummings, Jennifer E. ^{[2
]}

Bhargava, Mandeep ^{[2
]}

Burkhardt, David ^{[2
]}

Saliba, Walid

Raviele, Antonio ^{[3
]}

Natale, Andrea ^{[1
,5
,6
]}

机构：

[1] Stanford Univ, Med Ctr, Div Cardiol, Stanford, CA 94305 USA

[2] Cleveland Clin, Sect Pacing & Electrophysiol, Cleveland, OH 44106 USA

[3] Umberto I Hosp, Dept Cardiol, Venice, Italy

[4] Marin Gen Hosp, Dept Cardiol, Greenbrae, CA USA

[5] St Davids Med Ctr, Texas Cardiac Arrhythmia Inst, Austin, TX USA

[6] Case Western Reserve Univ, Cleveland, OH 44106 USA

来源：

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2008年 / 19卷 / 08期

关键词：

catheter ablation; atrial fibrillation; stroke; anticoagulation; elderly;

D O I：

10.1111/j.1540-8167.2008.01124.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Efficacy, Safety, and Outcome of AF Ablation in Septuagenarians. Aims: Catheter ablation is an effective treatment for atrial fibrillation (AF). The outcome of AF ablation in septuagenarians is not clear. Our aim was to evaluate success rate, outcome, and complication rate of AF ablation in septuagenarians. Methods and Results: We collected data from 174 consecutive patients over 75 years of age who underwent AF ablation from 2001 to 2006. AF was paroxysmal in 55%. High-risk CHADS score (>= 2) was present in 65% of the population. Over a mean follow-up of 20 +/- 14 months, 127 (73%) maintained sinus rhythm (SR) with a single procedure, whereas 47 patients had recurrence of AF. Twenty of them had a second ablation, successful in 16 (80%). Major acute complications included one CVA and one hemothorax (2/194 [1.0%]). During the follow-up, three patients had a CVA within the first 6 weeks after ablation. Warfarin was discontinued in 138 out 143 patients (96%) who maintained SR without AADs with no embolic event occurring over a mean follow-up of 16 +/- 12 months. Conclusion: AF ablation is a safe and effective treatment for AF in septuagenarians.

引用

页码：807 / 811

页数：5

共 23 条

[1]

[Anonymous], 1994, ARCH INTERN MED, V154, P1449

[2] Impact of atrial fibrillation on the risk of death [J].

Benjamin, EJ ;

Wolf, PA ;

D'Agostino, RB ;

Silbershatz, H ;

Kannel, WB ;

Levy, D .

CIRCULATION, 1998, 98 (10) :946-952

[3] Impact of age on the outcome of pulmonary vein isolation for atrial fibrillation using circular mapping technique and cooled-tip ablation catheter: A retrospective analysis [J].

Bhargava, M ;

Marrouche, NF ;

Martin, DO ;

Schweikert, RA ;

Saliba, W ;

Saad, EB ;

Bash, D ;

Williams-Andrews, M ;

Rossillo, A ;

Erciyes, D ;

Khaykin, Y ;

Burkhardt, JD ;

Joseph, G ;

Tchou, PJ ;

Natale, A .

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2004, 15 (01) :8-13

[4]

Blackshear JL, 1996, LANCET, V348, P633

[5] Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation [J].

Cappato, R ;

Calkins, H ;

Chen, SA ;

Davies, W ;

Iesaka, Y ;

Kalman, J ;

Kim, YH ;

Klein, G ;

Packer, D ;

Skanes, A .

CIRCULATION, 2005, 111 (09) :1100-1105

[6] PREVALENCE, AGE DISTRIBUTION, AND GENDER OF PATIENTS WITH ATRIAL-FIBRILLATION - ANALYSIS AND IMPLICATIONS [J].

FEINBERG, WM ;

BLACKSHEAR, JL ;

LAUPACIS, A ;

KRONMAL, R ;

HART, RG .

ARCHIVES OF INTERNAL MEDICINE, 1995, 155 (05) :469-473

[7] Prevalence of diagnosed atrial fibrillation in adults - National implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study [J].

Go, AS ;

Hylek, EM ;

Phillips, KA ;

Chang, YC ;

Henault, LE ;

Selby, JV ;

Singer, DE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (18) :2370-2375

[8] Changes in atrial fibrillation cycle length and inducibility during catheter ablation and their relation to outcome [J].

Haïssaguerre, M ;

Sanders, P ;

Hocini, M ;

Hsu, LF ;

Shah, DC ;

Scavée, C ;

Takahashi, Y ;

Rotter, M ;

Pasquié, JL ;

Garrigue, S ;

Clémenty, J ;

Jaïs, P .

CIRCULATION, 2004, 109 (24) :3007-3013

[9] Factors associated with ischemic stroke during aspirin therapy in atrial fibrillation - Analysis of 2012 participants in the SPAF I-III clinical trials [J].

Hart, RG ;

Pearce, LA ;

McBride, R ;

Rothbart, RM ;

Asinger, RW .

STROKE, 1999, 30 (06) :1223-1229

[10] Cerebrovascular complication associated with pulmonary vein ablation [J].

Kok, LC ;

Mangrum, JM ;

Haines, DE ;

Mounsey, JP .

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2002, 13 (08) :764-767

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