Highly efficient synthesis of 1,1-difluoro-2-substituted-1,3-dienes and dienynes from gem-difluorohomoallenyl bromide via palladium-catalyzed cross-coupling reactions

被引：33

作者：

Shen, QL ^{[1
]}

Hammond, GB ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem & Biochem, N Dartmouth, MA 02747 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 14期

关键词：

D O I：

10.1021/ol0160654

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A stable gem-difluoroallenylindium 1 is readily transformed to a potentially bifunctional electrophile 2, which can then undergo a transition-metal-promoted isomerization-cross coupling cascade to yield diene 3 and dienyne 4 in very high yields.

引用

页码：2213 / 2215

页数：3

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