Allotransplantation of the face: How close are we?

被引:25
作者
Siemionow, M [1 ]
Agaoglu, G [1 ]
机构
[1] Cleveland Clin Fdn, Dept Plast Surg A60, Cleveland, OH 44195 USA
关键词
D O I
10.1016/j.cps.2005.02.003
中图分类号
R61 [外科手术学];
学科分类号
摘要
Reconstruction of patients with severe facial disfigurements due to burns, trauma, or cancer is a challenging task for plastic surgeons. Currently, available reconstructive options rarely result in satisfactory functional and aesthetic outcomes. In this article the authors present the rationale and experimental basis for the introduction of composite facial allograft transplantation in humans. They outline the ethical, social, and media-related issues in facial allograft transplantation. © 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:401 / 409
页数:9
相关论文
共 37 条
[1]  
Bermúdez LE, 2002, PLAST RECONSTR SURG, V110, P1374, DOI 10.1097/00006534-200210000-00044
[2]   TISSUE EXPANSION IN RECONSTRUCTION [J].
BOYD, JB .
SOUTHERN MEDICAL JOURNAL, 1987, 80 (04) :430-432
[3]  
Cendales L, 2000, TRANSPLANTATION, V69, pS295
[4]   Tolerance induction in composite facial allograft transplantation in the rat model [J].
Demir, Y ;
Ozmen, S ;
Klimczak, A ;
Mukherjee, AL ;
Siemionow, M .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2004, 114 (07) :1790-1801
[5]   Human hand allograft: report on first 6 months [J].
Dubernard, JM ;
Owen, E ;
Herzberg, G ;
Lanzetta, M ;
Martin, X ;
Kapila, H ;
Dawahra, M ;
Hakim, NS .
LANCET, 1999, 353 (9161) :1315-1320
[6]  
EROL OO, 1976, PLAST RECONSTR SURG, V58, P470
[7]   Medical progress - Skin cancers after organ transplantation [J].
Euvrard, S ;
Kanitakis, J ;
Claudy, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (17) :1681-1691
[8]   The effect of the immunosuppressant FK 506 on peripheral nerve regeneration following nerve grafting [J].
Fansa, H ;
Keilhoff, G ;
Altmann, S ;
Plogmeier, K ;
Wolf, G ;
Schneider, W .
JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME, 1999, 24B (01) :38-42
[9]  
Francois CG, 2000, MICROSURG, V20, P360, DOI 10.1002/1098-2752(2000)20:8<360::AID-MICR4>3.3.CO
[10]  
2-5