Biphenyls as surrogates of the steroidal backbone.: Part 1:: Synthesis and estrogen receptor affinity of an original series of polysubstituted biphenyls

被引：15

作者：

Lesuisse, D

Albert, E

Bouchoux, F

Cérède, E

Lefrançois, JM

Levif, MO

Tessier, S

Tric, B

Teutsch, G

机构：

[1] Aventis, Med Chem, F-93235 Romainville, France

[2] Aventis, Bone Dis Grp, F-93235 Romainville, France

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 13期

关键词：

D O I：

10.1016/S0960-894X(01)00267-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In the course of a programme aimed at discovering nea ligands of the estrogen receptor, we explored a series of substituted biphenyls. Their synthesis and binding affinity are described. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1709 / 1712

页数：4

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