Intramolecular palladium-catalyzed direct arylation of alkenyl triflates

被引：34

作者：

Cruz, Ana C. F.

Miller, Neil D.

Willis, Michael C. ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England

[3] GlaxoSmithKline, Harlow CM19 5AW, Essex, England

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 21期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1021/ol702044z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A catalyst generated from Pd(OAC)(2) and dppp is effective for the direct intramolecular arylation of alkenyl triflates. Conjugated alkene-arene-containing carbocycles are produced in good yield. The process tolerates a variety of aryl substituents as well a simple heteroaryl groups. Electron-deficient aryl rings deliver faster reactions.

引用

收藏

页码：4391 / 4393

页数：3

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