Low-temperature method for enhancement of enantioselectivity in the lipase-catalyzed kinetic resolutions of solketal and some chiral alcohols

被引：71

作者：

Sakai, T ^{[1
]}

Kishimoto, T ^{[1
]}

Tanaka, Y ^{[1
]}

Ema, T ^{[1
]}

Utaka, M ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7008530, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 43期

关键词：

acylation; enantiospecificity; enzymes and enzyme reactions; resolution;

D O I：

10.1016/S0040-4039(98)01747-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Low-temperature method (-40 degrees C at best) for enhancement of the enantioselectivity in a lipase-catalyzed transesterification was proved to be widely applicable to primary and secondary alcohols and enabled theoretical prediction of the course of enhancement of the enantioselectivity physicochemically, (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7881 / 7884

页数：4

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