Assessment of platelet response to clopidogrel through measurement of ADP-induced Akt phosphorylation

被引:3
作者
Carrie, D. [1 ]
Garcia, C. [4 ]
Gratacap, M. P. [2 ]
Voisin, S. [4 ]
Payrastre, B. [2 ,4 ]
Sie, P. [3 ,4 ]
机构
[1] CHU Toulouse, Serv Cardiol, Toulouse, France
[2] Ctr Physiopathol Toulouse Purpan, INSERM, Dept Oncogenese Signalisat & Innovat Therapeut, U563, Toulouse, France
[3] INSERM, U858, F-31423 Toulouse, France
[4] CHU Toulouse, Hematol Lab, Toulouse, France
关键词
REACTIVITY; THROMBOSIS; PATHWAYS;
D O I
10.1111/j.1538-7836.2009.03485.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1411 / 1413
页数:3
相关论文
共 10 条
[1]   The significance of vasodilator-stimulated phosphoprotein for risk stratification of stent thrombosis [J].
Blindt, Ruediger ;
Stellbrink, Katja ;
de Taeye, Anita ;
Mueller, Robert ;
Kiefer, Paul ;
Yagmur, Eray ;
Weber, Christian ;
Kelm, Malte ;
Hoffmann, Rainer .
THROMBOSIS AND HAEMOSTASIS, 2007, 98 (06) :1329-1334
[2]   Is face-view only enough for the aesthetic evaluation of breast cancer conservative treatment (BCCT)? [J].
Cardoso, M. J. ;
Cardoso, J. S. ;
Vrieling, C. ;
Christie, D. ;
Joahensen, J. ;
Costa, S. ;
Almeida, T. .
EJC SUPPLEMENTS, 2007, 5 (03) :6-6
[3]   Resistance to antiplatelet drugs: molecular mechanisms and laboratory detection [J].
Cattaneo, M. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 :230-237
[4]   High post-treatment platelet reactivity is associated with a high incidence of myonecrosis after stenting for non-ST elevation acute coronary syndromes [J].
Cuisset, Thomas ;
Frere, Corinne ;
Quilici, Jacques ;
Morange, Pierre-Emmanuel ;
Nait-Saidi, Lyassine ;
Mielot, Christopher ;
Bali, Laurent ;
Lambert, Marc ;
Alessi, Marie-Christine ;
Bonnet, Jean-Louis .
THROMBOSIS AND HAEMOSTASIS, 2007, 97 (02) :282-287
[5]   FcγRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation [J].
Gratacap, MP ;
Hérault, JP ;
Viala, C ;
Ragab, A ;
Savi, P ;
Herbert, JM ;
Chap, H ;
Plantavid, M ;
Payrastre, B .
BLOOD, 2000, 96 (10) :3439-3446
[6]   Akt activation in platelets depends on Gi signaling pathways [J].
Kim, S ;
Jin, JG ;
Kunapuli, SP .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (06) :4186-4195
[7]   Monitoring platelet inhibition after clopidogrel with the VerifyNow-P2Y1® rapid analyzer:: The VERIfy Thrombosis risk ASsessment (VERITAS) study [J].
Malinin, Alex ;
Pokov, Alex ;
Spergling, Malcolm ;
Defranco, Anthony ;
Schwartz, Kenneth ;
Schwartz, Dianne ;
Mahmud, Ehtisham ;
Atar, Dan ;
Serebruany, Victor .
THROMBOSIS RESEARCH, 2007, 119 (03) :277-284
[8]   Point-of-care measurement of clopidogrel responsiveness predicts clinical outcome in patients undergoing percutaneous coronary intervention - Results of the ARMYDA-PRO (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Platelet Reactivity Predicts Outcome) Study [J].
Patti, Giuseppe ;
Nusca, Annunziata ;
Mangiacapra, Fabio ;
Gatto, Laura ;
D'Ambrosio, Andrea ;
Di Sciascio, Germano .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (14) :1128-1133
[9]   Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation [J].
Price, Matthew J. ;
Endemann, Sarah ;
Gollapudi, Raghava R. ;
Valencia, Rafael ;
Stinis, Curtiss T. ;
Levisay, Justin P. ;
Ernst, Alissa ;
Sawhney, Neil S. ;
Schatz, Richard A. ;
Teirstein, Paul S. .
EUROPEAN HEART JOURNAL, 2008, 29 (08) :992-1000
[10]   Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets - Definition and detection of ticlopidine/clopidogrel effects [J].
Schwarz, UR ;
Geiger, J ;
Walter, U ;
Eigenthaler, M .
THROMBOSIS AND HAEMOSTASIS, 1999, 82 (03) :1145-1152