Nakiterpiosin, a novel cytotoxic C-nor-D-homosteroid from the Okinawan sponge Terpios hoshinota

被引：34

作者：

Teruya, T ^{[1
]}

Nakagawa, S ^{[1
]}

Koyama, T ^{[1
]}

Suenaga, K ^{[1
]}

Kita, M ^{[1
]}

Uemura, D ^{[1
]}

机构：

[1] Nagoya Univ, Dept Chem, Grad Sch Sci, Nagoya, Aichi 4648602, Japan

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(03)01267-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel cytotoxic compound, nakiterpiosin (1), was isolated from the Okinawan sponge Terpios hoshinota. Its structure was determined by spectroscopic analysis. The absolute stereostructure of 1 was also determined by a modified Mosher's method. Nakiterpiosin showed potent cytotoxicity against P388 cells. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：5171 / 5173

页数：3

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