Availability of the epinephrine autoinjector at school in children with peanut allergy

被引:47
作者
Ben-Shoshan, Moshe [1 ]
Kagan, Rhoda [2 ]
Primeau, Marie-Noel [1 ]
Alizadehfar, Reza [1 ]
Verreault, Nina [1 ]
Yu, Joyce W. [1 ]
Nicolas, Nathalie [3 ]
Joseph, Lawrence [3 ,4 ]
Turnbull, Elizabeth [3 ]
Dufresne, Claire [5 ]
Pierre, Yvan St. [3 ]
Clarke, Ann [3 ,6 ]
机构
[1] McGill Univ, Ctr Hlth, Div Pediat Allergy & Clin Immunol, Montreal, PQ, Canada
[2] N York Gen Hosp, Div Clin Immunol & Allergy, Toronto, ON, Canada
[3] McGill Univ, Ctr Hlth, Div Clin Epidemiol, Montreal, PQ, Canada
[4] McGill Univ, Dept Epidemiol & Biostat, Montreal, PQ, Canada
[5] Assoc Quebecoise Allergies Alimentaires, Montreal, PQ, Canada
[6] McGill Univ, Ctr Hlth, Div Clin Immunol & Allergy, Montreal, PQ, Canada
关键词
D O I
10.1016/S1081-1206(10)60056-7
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: Peanut allergy accounts for most severe food-related allergic reactions, and accidental exposures are frequent. Delayed administration of epinephrine and the allergic individual's failure to personally carry epinephrine contribute to fatal outcomes. Objectives: To describe epinephrine autoinjector availability at school and to determine factors that might affect autoinjector availability in children allergic to peanut. Methods: Two hundred seventy-one children with peanut allergy living in Quebec were queried about their autoinjector. Logistic regression models were used to select factors associated with device availability. Results: Four of 271 children diagnosed as having peanut allergy were not prescribed autoinjectors. Forty-eight percent of the children did not carry the autoinjector with them at school. In 78.0% of those, the autoinjector was located in the nurse's or another school office, which was staffed by a full-time nurse only in 18.5%. Of all the respondents, those administered epinephrine for a previous reaction (odds ratio [OR], 2.7; 95% confidence interval [CI], 1.3-5.7), older children (OR, 1.1; 95% CI, 1.0-1.2), and those living only with their mother (OR, 3.4; 95% CI, 1.0-11 1.0) were more likely to carry the autoinjector with them at school. Of children 7 years or older, those who experienced a severe reaction were more likely to carry their autoinjector (OR, 3.3; 95% CI, 1.4-8.1). Conclusions: Almost 50% of children allergic to peanut might experience a delay in anaphylaxis treatment due to limited access to their device. More education is required regarding the importance of a readily available autoinjector.
引用
收藏
页码:570 / 575
页数:6
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