Adult stem cells and neurogenesis: Historical roots and state of the art

被引:34
作者
Geuna, S [1 ]
Borrione, P [1 ]
Fornaro, M [1 ]
Giacobini-Robecchi, MG [1 ]
机构
[1] Univ Turin, Osped San Luigi, Dipartimento Sci Clin & Biol, I-10043 Orbassano, TO, Italy
来源
ANATOMICAL RECORD | 2001年 / 265卷 / 03期
关键词
adult stem cell; developmental stem cell; Duchenne muscular dystrophy; dystrophin; embryonic stem cell; ES; neurogenesis; Parkinson; proliferation;
D O I
10.1002/ar.1135
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Over the last few years, an impressive number of papers have addressed the stem cell issue. However, as often occurs when a scientific subject undergoes a period of fast growth, some confusion is generated. To help reduce the existing uncertainty, this paper focuses on the concept of adult stem cells in relation to the classification of cell populations on the basis their proliferative behavior. Particular attention is dedicated to adult neural stem cells, an issue that has recently seen the most amazing advances. Finally, the concept of adult stem cells is differentiated from that of developmental stem cells in relation to the employment of stem cells for transplantation therapies. Anat Rec (New Anat) 265:132-141, 2001. (C) 2001 Wiley-Liss, Inc.
引用
收藏
页码:132 / +
页数:10
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